Anti-PDE6B antibody {Biotin} (STJ502361)

SKU:
STJ502361-100

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Host: Rabbit
Applications: ELISA/CM/ICC/IF/IHC/WB
Reactivity: Bovine/Human/Mouse/Pig/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE6B is suitable for use in ELISA, Confocal Microscopy, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IHC: 1:200
ICC: 1:200
IF: 1:200
CFM: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE6B
Gene ID: 5158
Uniprot ID: PDE6B_HUMAN
Immunogen: Synthetic cyclic petide common to all PDE6 Beta variants
Function Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal.
Protein Name Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta
Gmp-Pde Beta
Database Links Reactome: R-HSA-2485179
Reactome: R-HSA-2514859
Reactome: R-HSA-4086398
Cellular Localisation Membrane
Lipid-Anchor
Cell Projection
Cilium
Photoreceptor Outer Segment
Alternative Antibody Names Anti-Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta antibody
Anti-Gmp-Pde Beta antibody
Anti-PDE6B antibody
Anti-PDEB antibody

Information sourced from Uniprot.org

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