Anti-PDE4B antibody (N-Term) {Biotin} (STJ502301)

SKU:
STJ502301-100

£546.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE4B (N-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.68 µg/µl
Dilution Range: WB: 1:500-1:1, 000
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:350
IHC: 1:250
ICC: 1:250
IF: 1:250
CFM: 1:250
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE4B
Gene ID: 5142
Uniprot ID: PDE4B_HUMAN
Immunogen Region: N-Term
Specificity: Does not cross-react with other PDE family members such as PDE4A, PDE4C, or PDE4D.
Immunogen: Synthetic peptide common to all PDE4B subtypes taken near N-terminal
Tissue Specificity Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Protein Name Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b
Dpde4
Pde32
Database Links Reactome: R-HSA-180024 Q07343-3
Cellular Localisation Isoform Pde4b5: Cytoplasm
Cell Membrane
Alternative Antibody Names Anti-Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b antibody
Anti-Dpde4 antibody
Anti-Pde32 antibody
Anti-PDE4B antibody
Anti-DPDE4 antibody

Information sourced from Uniprot.org

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