• Western blot with Anti-PDE3B Antibody (STJ502269) on PD38 peptide. Antibody at 1:500 dilution in buffer.

Anti-PDE3B antibody (1060-1110) (STJ502269)

SKU:
STJ502269-100

£481.50
Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: ELISA/IP/WB
Reactivity: Chicken/Human/Monkey/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PDE3B (1060-1110) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:500
ICC: 1:500
IF: 1:500
CFM: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Pde3b
Gene ID: 29516
Uniprot ID: PDE3B_RAT
Immunogen Region: 1060-1110
Specificity: Does not cross react with PDE4A variants nor with any other PDE famly members. This antibody will recognize PDE3B variants.
Immunogen: Synthetic peptide taken within amino acid region 1060-1110 on human PDE3B protein.
Tissue Specificity Abundant in adipose tissues.
Post Translational Modifications Phosphorylation at Ser-279 mediates insulin-induced activation of PDE3B.
Function Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling. Controls cardiac contractility by reducing cAMP concentration in cardiocytes.
Protein Name Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b
Cgi Pde
Cyclic Gmp-Inhibited Phosphodiesterase B
Cgi-Pde B
Rcgipl
Database Links Reactome: R-RNO-165160
Reactome: -RNO-418555
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b antibody
Anti-Cgi Pde antibody
Anti-Cyclic Gmp-Inhibited Phosphodiesterase B antibody
Anti-Cgi-Pde B antibody
Anti-Rcgipl antibody
Anti-Pde3b antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance