• Immunohistochemistry analysis of paraffin-embedded rat brain using PDE1B antibody (STJ24930) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using PDE1B antibody (STJ24930) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-PDE1B antibody (190-536) (STJ24930)

SKU:
STJ24930

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE1B (190-536) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE1B
Gene ID: 5153
Uniprot ID: PDE1B_HUMAN
Immunogen Region: 190-536
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1).
Immunogen Sequence: RHNLISRFKIPTVFLMSFLD ALETGYGKYKNPYHNQIHAA DVTQTVHCFLLRTGMVHCLS EIELLAIIFAAAIHDYEHTG TTNSFHIQTKSECAIVYNDR SVLENHHISSVFRLMQDDEM NIFINLTKDEFVELRALVIE MVLATDMSCHFQQVKTMKTA LQQLERIDKPKALSLLLHAA DISHPTKQWLVHSRWTKALM EEFFRQGDKEAELGLPFSPL CDRTSTLVAQSQIGFIDFI
Function Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
Protein Name Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1b
Cam-Pde 1b
63 Kda Cam-Pde
Database Links Reactome: R-HSA-111957
Reactome: R-HSA-418457
Reactome: R-HSA-418555
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1b antibody
Anti-Cam-Pde 1b antibody
Anti-63 Kda Cam-Pde antibody
Anti-PDE1B antibody
Anti-PDES1B antibody

Information sourced from Uniprot.org

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