| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDE1B |
| Gene ID: | 5153 |
| Uniprot ID: | PDE1B_HUMAN |
| Immunogen Region: | 190-536 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1). |
| Immunogen Sequence: | RHNLISRFKIPTVFLMSFLD ALETGYGKYKNPYHNQIHAA DVTQTVHCFLLRTGMVHCLS EIELLAIIFAAAIHDYEHTG TTNSFHIQTKSECAIVYNDR SVLENHHISSVFRLMQDDEM NIFINLTKDEFVELRALVIE MVLATDMSCHFQQVKTMKTA LQQLERIDKPKALSLLLHAA DISHPTKQWLVHSRWTKALM EEFFRQGDKEAELGLPFSPL CDRTSTLVAQSQIGFIDFI |
| Function | Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1bCam-Pde 1b63 Kda Cam-Pde |
| Database Links | Reactome: R-HSA-111957Reactome: R-HSA-418457Reactome: R-HSA-418555 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1b antibodyAnti-Cam-Pde 1b antibodyAnti-63 Kda Cam-Pde antibodyAnti-PDE1B antibodyAnti-PDES1B antibody |
Information sourced from Uniprot.org