• STJ71246 (1µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PDE11A antibody (Internal) (STJ71246)

SKU:
STJ71246-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PDE11A (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.5-1.5µg/ml
IHC-10µg/ml
ELISA-antibody detection limit dilution 1:2000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PDE11A
Gene ID: 50940
Uniprot ID: PDE11_HUMAN
Immunogen Region: Internal
Accession Number: NP_058649.3 ; NP_001070665.1; NP_001070826.1; NP_001070664.1
Specificity: This antibody is expected to recognise all four reported isoforms (NP_058649.3 ; NP_001070665.1; NP_001070826.1; NP_001070664.1).
Immunogen Sequence: NSFKESMEKSSYSD
Function Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
Protein Name Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a
Camp And Cgmp Phosphodiesterase 11a
Database Links Reactome: R-HSA-418457
Reactome: R-HSA-418555
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a antibody
Anti-Camp And Cgmp Phosphodiesterase 11a antibody
Anti-PDE11A antibody

Information sourced from Uniprot.org

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