| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phosducin-like protein 3 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDCL3 |
| Gene ID: | 79031 |
| Uniprot ID: | PDCL3_HUMAN |
| Specificity: | This antibody detects endogenous levels of PDCL3 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human PDCL3 |
| Post Translational Modifications | N-terminal methionine acetylation destabilizes the protein. |
| Function | Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding. Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes. Modulates the activation of caspases during apoptosis. |
| Protein Name | Phosducin-Like Protein 3HtphlpPhpl3Viral Iap-Associated Factor 1Viaf-1 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Phosducin-Like Protein 3 antibodyAnti-Htphlp antibodyAnti-Phpl3 antibodyAnti-Viral Iap-Associated Factor 1 antibodyAnti-Viaf-1 antibodyAnti-PDCL3 antibodyAnti-PhLP2A antibodyAnti-VIAF1 antibody |
Information sourced from Uniprot.org