Immunohistochemistry analysis of paraffin-embedded rat heart using PD-L2/CD273 Rabbit monoclonal antibody (STJ11105086) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-PDCD1LG2 antibody [S5086RM] (STJ11105086)

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STJ11105086
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S5086RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDCD1LG2
Gene ID: 80380
Uniprot ID: PD1L2_HUMAN
Specificity: Recombinant protein of human PD-L2/CD273.
Tissue Specificity Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Antibody Names Anti-Programmed Cell Death 1 Ligand 2 antibody
Anti-Pd-1 Ligand 2 antibody
Anti-Pd-L2 antibody
Anti-Pdcd1 Ligand 2 antibody
Anti-Programmed Death Ligand 2 antibody
Anti-Butyrophilin B7-Dc antibody
Anti-B7-Dc antibody
Anti-Cd Antigen Cd273 antibody
Anti-PDCD1LG2 antibody
Anti-B7DC antibody
Anti-CD273 antibody
Anti-PDCD1L2 antibody
Anti-PDL2 antibody

Information sourced from Uniprot.org

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