PD-L2 antibody immunohistochemistry human prostate tissue STJA0033387

Anti-PD-L2 antibody [ZN223] (STJA0033387)

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STJA0033387
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Short Description :Mouse monoclonal anti-PD-L2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :ZN223
Isotype:IgG1
Conjugation:Unconjugated
Concentration:0.5-1.0 mg/mL
Purification:Affinity Chromatography
Dilution Range:IHC 1:50-1:100
Formulation:PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:PDCD1LG2
Gene ID:80380
Uniprot ID:PD1L2_HUMAN
Immunogen:Full length human recombinant protein of human PDCD1LG2 (NP_079515) produced in HEK293T cell.
Tissue Specificity Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Antibody Names Anti-Programmed Cell Death 1 Ligand 2 antibody
Anti-Pd-1 Ligand 2 antibody
Anti-Pd-L2 antibody
Anti-Pdcd1 Ligand 2 antibody
Anti-Programmed Death Ligand 2 antibody
Anti-Butyrophilin B7-Dc antibody
Anti-B7-Dc antibody
Anti-Cd Antigen Cd273 antibody
Anti-PDCD1LG2 antibody
Anti-B7DC antibody
Anti-CD273 antibody
Anti-PDCD1L2 antibody
Anti-PDL2 antibody

Information sourced from Uniprot.org

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