| Host: | Mouse |
| Applications: | LF/CLIA/FIA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-PCT (67-95aa) for use in LF, CLIA and FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 4005 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Immunogen Region: | 67-95aa |
| Specificity: | Antibody recognizes human procalcitonin (PCT). Not determined |
| Immunogen: | Anti-h PCT 4005 antibody recognizes the calcitonin domain of procalcitonin, i.e. the region Met (67)-Arg (95) , as calculated from the peptide sequence of the mature PCT protein, without the signal sequence. The most critical amino acids for binding |
| Background | Procalcitonin (PCT) is a precursor protein of the hormone calcitonin, produced by the thyroid gland. It is a 116 amino acid protein that is cleaved intracellularly to form three peptides: N-terminal procalcitonin, calcitonin, and katacalcin. In healthy individuals, only the calcitonin polypeptide is secreted into the bloodstream, and PCT serum levels are very low. However, in patients with systemic infections, and especially sepsis, serum PCT levels rise rapidly. |
Information sourced from Uniprot.org
