| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Neuroendocrine convertase 1 (125-175 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PCSK1 |
| Gene ID: | 5122 |
| Uniprot ID: | NEC1_HUMAN |
| Immunogen Region: | 125-175 aa |
| Specificity: | This antibody detects endogenous levels of NEC1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human NEC1 at the amino acid range 125-175 |
| Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. |
| Protein Name | Neuroendocrine Convertase 1Nec 1Prohormone Convertase 1Proprotein Convertase 1Pc1 |
| Database Links | Reactome: R-HSA-209952Reactome: R-HSA-264876Reactome: R-HSA-381771Reactome: R-HSA-400511Reactome: R-HSA-422085 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleLocalized In The Secretion Granules |
| Alternative Antibody Names | Anti-Neuroendocrine Convertase 1 antibodyAnti-Nec 1 antibodyAnti-Prohormone Convertase 1 antibodyAnti-Proprotein Convertase 1 antibodyAnti-Pc1 antibodyAnti-PCSK1 antibodyAnti-NEC1 antibody |
Information sourced from Uniprot.org
