Anti-PCBD1 antibody [R41-2R-5] (STJA0035589)

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STJA0035589
€166.88 - €351.88
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Host: Rabbit
Applications: WB/IHC-P
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-PCBD1 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R41-2R-5
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
IHC 1:100-1:200
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: PCBD1
Gene ID: 5092
Uniprot ID: PHS_HUMAN
Immunogen: A synthesized peptide derived from human PCBD1
Function Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription.
Protein Name Pterin-4-Alpha-Carbinolamine Dehydratase
Phs
4-Alpha-Hydroxy-Tetrahydropterin Dehydratase
Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha
Dcoh
Dimerization Cofactor Of Hnf1
Phenylalanine Hydroxylase-Stimulating Protein
Pterin Carbinolamine Dehydratase
Pcd
Database Links Reactome: R-HSA-8964208
Cellular Localisation Cytoplasm
Nucleus
Recruited To The Nucleus Through The Interaction With Hnf1b
Alternative Antibody Names Anti-Pterin-4-Alpha-Carbinolamine Dehydratase antibody
Anti-Phs antibody
Anti-4-Alpha-Hydroxy-Tetrahydropterin Dehydratase antibody
Anti-Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha antibody
Anti-Dcoh antibody
Anti-Dimerization Cofactor Of Hnf1 antibody
Anti-Phenylalanine Hydroxylase-Stimulating Protein antibody
Anti-Pterin Carbinolamine Dehydratase antibody
Anti-Pcd antibody
Anti-PCBD1 antibody
Anti-DCOH antibody
Anti-PCBD antibody

Information sourced from Uniprot.org

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