Anti-PBK IP antibody [SAA0214] (STJA0018729)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
STJA0018729
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General Information

Short DescriptionMouse monoclonal Lymphokine-Activated Killer T-Cell-Originated Protein Kinase antibody for use in ELISA, IF, IP and IP-MS in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA/IF/IP/IP-MS
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS

Product Properties

ClonalityMonoclonal
Clone IDSAA0214
IsotypeIgG1
ConjugationUnconjugated
Concentration1 mg/mL
PurificationProtein A/G purified from cell culture supernatant
Formulation0.01M PBS, pH 7.4.
Storage InstructionSuitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months

Target Information

Gene SymbolPBK
Gene ID55872
Uniprot IDTOPK_HUMAN

Additional Info

Post Translational Modifications Phosphorylated.in a cell-cycle dependent manner at mitosis.
Function Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Protein Name Lymphokine-Activated Killer T-Cell-Originated Protein Kinase
Cancer/Testis Antigen 84
Ct84
Mapkk-Like Protein Kinase
Nori-3
Pdz-Binding Kinase
Spermatogenesis-Related Protein Kinase
Spk
T-Lak Cell-Originated Protein Kinase
Database Links
Cellular Localisation
Alternative Antibody Names Anti-Lymphokine-Activated Killer T-Cell-Originated Protein Kinase antibody
Anti-Cancer/Testis Antigen 84 antibody
Anti-Ct84 antibody
Anti-Mapkk-Like Protein Kinase antibody
Anti-Nori-3 antibody
Anti-Pdz-Binding Kinase antibody
Anti-Spermatogenesis-Related Protein Kinase antibody
Anti-Spk antibody
Anti-T-Lak Cell-Originated Protein Kinase antibody
Anti-PBK antibody
Anti-TOPK antibody

Information sourced from Uniprot.org

Citations

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