Anti-PAX8 antibody (Internal) (STJ70826)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-PAX8 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB-Trf |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: In transfected HEK293 transiently expressing PAX8A a band of approx. 55kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.5-1.5ยตg/ml |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PAX8 |
| Gene ID | 7849 |
| Uniprot ID | PAX8_HUMAN |
| Accession Number | NP_003457.1; NP_039245.1; NP_039246.1; NP_039247.1; NP_054698.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | AQPGSDKRKMDD |
| Specificity | This antibody is expected to recognise all reported isoforms (NP_003457.1; NP_039245.1; NP_039246.1; NP_039247.1; NP_054698.1) |
Additional Info
| Function | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. |
| Protein Name | Paired Box Protein Pax-8 |
| Database Links | Reactome: R-HSA-9761174Reactome: R-HSA-9830364 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-8 antibodyAnti-PAX8 antibody |
Information sourced from Uniprot.org