| Host: | Goat |
| Applications: | Pep-ELISA/WB-Trf |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PAX8 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: In transfected HEK293 transiently expressing PAX8A a band of approx. 55kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.5-1.5µg/ml |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PAX8 |
| Gene ID: | 7849 |
| Uniprot ID: | PAX8_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_003457.1; NP_039245.1; NP_039246.1; NP_039247.1; NP_054698.1 |
| Specificity: | This antibody is expected to recognise all reported isoforms (NP_003457.1; NP_039245.1; NP_039246.1; NP_039247.1; NP_054698.1) |
| Immunogen Sequence: | AQPGSDKRKMDD |
| Function | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. |
| Protein Name | Paired Box Protein Pax-8 |
| Database Links | Reactome: R-HSA-9761174Reactome: R-HSA-9830364 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-8 antibodyAnti-PAX8 antibody |
Information sourced from Uniprot.org
