• Immunohistochemistry analysis of PAX8 in paraffin-embedded human thyroid cancer using PAX8 Rabbit monoclonal antibody (STJ11104737) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-PAX8 antibody (200-300) [S4737RM] (STJ11104737)

SKU:
STJ11104737

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Host: Rabbit
Applications: IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Paired Box Protein Pax-8 (200-300) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S4737RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PAX8
Gene ID: 7849
Uniprot ID: PAX8_HUMAN
Immunogen Region: 200-300
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PAX8 (NP_003457.1).
Immunogen Sequence: DSDQDSCRLSIDSQSSSSGP RKHLRTDAFSQHHLEPLECP FERQHYPEAYASPSHTKGEQ GLYPLPLLNSTLDDGKATLT PSNTPLGRNLSTHQTYPVVA D
Tissue Specificity Expressed in the excretory system, thyroid gland and Wilms tumors.
Function Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells.
Protein Name Paired Box Protein Pax-8
Database Links Reactome: R-HSA-9761174
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Paired Box Protein Pax-8 antibody
Anti-PAX8 antibody

Information sourced from Uniprot.org

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