| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAX7 |
| Gene ID: | 5081 |
| Uniprot ID: | PAX7_HUMAN |
| Immunogen Region: | 289-518 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 289-518 of human PAX7 (NP_039236.1). |
| Immunogen Sequence: | GFPPTGMPTLPPYQLPDSTY PTTTISQDGGSTVHRPQPLP PSTMHQGGLAAAAAAADTSS AYGARHSFSSYSDSFMNPAA PSNHMNPVSNGLSPQVMSIL GNPSAVPPQPQADFSISPLH GGLDSATSISASCSQRADSI KPGDSLPTSQAYCPPTYSTT GYSVDPVAGYQYGQYGQSEC LVPWASPVPIPSPTPRASCL FMESYKVVSGWGMSISQMEK LKSSQMEQFT |
| Post Translational Modifications | Acetylation at Lys-105 and Lys-139 by KAT8 is required for high-level transcription factor activity. Deacetylated by SIRT2. |
| Function | Transcription factor that is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration. |
| Protein Name | Paired Box Protein Pax-7Hup1 |
| Database Links | Reactome: R-HSA-9834899 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-7 antibodyAnti-Hup1 antibodyAnti-PAX7 antibodyAnti-HUP1 antibody |
Information sourced from Uniprot.org