Host: | Rabbit |
Applications: | ELISA/WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-PAX4 (250-300) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.92-1.25 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | PAX4Uniprot ID=PAX4_HUMAN" |
Immunogen Region: | 250-300 |
Immunogen: | Synthetic peptide taken within amino acid region 250-300, corresponding to unique amino acid sequence on PAX4 protein. |
Function | Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity. |
Protein Name | Paired Box Protein Pax-4 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Paired Box Protein Pax-4 antibody Anti-PAX4 antibody |
Information sourced from Uniprot.org