Host: |
Rabbit |
Applications: |
WB/IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-PAX3 (1-479) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PAX3 |
Gene ID: |
5077 |
Uniprot ID: |
PAX3_HUMAN |
Immunogen Region: |
1-479 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-479 of human PAX3 (NP_852122.1). |
Immunogen Sequence: |
MTTLAGAVPRMMRPGPGQNY PRSGFPLEVSTPLGQGRVNQ LGGVFINGRPLPNHIRHKIV EMAHHGIRPCVISRQLRVSH GCVSKILCRYQETGSIRPGA IGGSKPKQVTTPDVEKKIEE YKRENPGMFSWEIRDKLLKD AVCDRNTVPSVSSISRILRS KFGKGEEEEADLERKEAEES EKKAKHSIDGILSERASAPQ SDEGSDIDSEPDLPLKRKQR RSRTTFTAEQLEELER |
Function | Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10. |
Protein Name | Paired Box Protein Pax-3Hup2 |
Database Links | Reactome: R-HSA-3214847 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Paired Box Protein Pax-3 antibodyAnti-Hup2 antibodyAnti-PAX3 antibodyAnti-HUP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance