| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAX3 |
| Gene ID: | 5077 |
| Uniprot ID: | PAX3_HUMAN |
| Immunogen Region: | 1-479 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human PAX3 (NP_852122.1). |
| Immunogen Sequence: | MTTLAGAVPRMMRPGPGQNY PRSGFPLEVSTPLGQGRVNQ LGGVFINGRPLPNHIRHKIV EMAHHGIRPCVISRQLRVSH GCVSKILCRYQETGSIRPGA IGGSKPKQVTTPDVEKKIEE YKRENPGMFSWEIRDKLLKD AVCDRNTVPSVSSISRILRS KFGKGEEEEADLERKEAEES EKKAKHSIDGILSERASAPQ SDEGSDIDSEPDLPLKRKQR RSRTTFTAEQLEELER |
| Function | Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10. |
| Protein Name | Paired Box Protein Pax-3 Hup2 |
| Database Links | Reactome: R-HSA-3214847 Reactome: R-HSA-9834899 Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-3 antibody Anti-Hup2 antibody Anti-PAX3 antibody Anti-HUP2 antibody |
Information sourced from Uniprot.org