| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Alpha-Parvin (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PARVA |
| Gene ID: |
55742 |
| Uniprot ID: |
PARVA_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PARVA (NP_060692.3). |
| Immunogen Sequence: |
MATSPQKSPSVPKSPTPKSP PSRKKDDSFLGKLGGTLARR KKAKEVSELQEEGMNAINLP LSPIPFELDPEDTMLEENEV RTMVDPNSRSDPKLQELMKV |
| Tissue Specificity | Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. |
| Function | Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development. Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishment of cell polarity, cell adhesion, cell spreading, and directed cell migration. |
| Protein Name | Alpha-ParvinActopaxinCh-IlkbpCalponin-Like Integrin-Linked Kinase-Binding ProteinMatrix-Remodeling-Associated Protein 2 |
| Database Links | Reactome: R-HSA-446343Reactome: R-HSA-446353Reactome: R-HSA-446388 |
| Cellular Localisation | Cell JunctionFocal AdhesionCell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonMyofibrilSarcomereZ LineConstituent Of Focal AdhesionsAssociates With The Actin Cytoskeleton |
| Alternative Antibody Names | Anti-Alpha-Parvin antibodyAnti-Actopaxin antibodyAnti-Ch-Ilkbp antibodyAnti-Calponin-Like Integrin-Linked Kinase-Binding Protein antibodyAnti-Matrix-Remodeling-Associated Protein 2 antibodyAnti-PARVA antibodyAnti-MXRA2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
