• Western blot with Anti-PAR1 Antibody (STJ502110) with PAR1 peptide. Antibody at 1:500 dilution in buffer.

Anti-PAR1 antibody (390-440) (STJ502110)

SKU:
STJ502110-100

£441.50
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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PAR1 (390-440) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.63-0.65 µg/µl
Dilution Range: WB: 1:250
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: F2r
Gene ID: 14062
Uniprot ID: PAR1_MOUSE
Immunogen Region: 390-440
Immunogen: Synthetic peptide taken within amino acid region 390-440 on mouse PAR1 protein.
Post Translational Modifications Proteolytic cleavage by thrombin generates a new N-terminus that functions as a tethered ligand. Also proteolytically cleaved by cathepsin CTSG. Phosphorylated in the C-terminal tail.probably mediating desensitization prior to the uncoupling and internalization of the receptor.
Function High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Protein Name Proteinase-Activated Receptor 1
Par-1
Thrombin Receptor
Database Links Reactome: R-MMU-140875
Reactome: -MMU-375276
Reactome: -MMU-416476
Reactome: -MMU-456926
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Proteinase-Activated Receptor 1 antibody
Anti-Par-1 antibody
Anti-Thrombin Receptor antibody
Anti-F2r antibody
Anti-Cf2r antibody
Anti-Par1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance