| Short Description : | Rabbit polyclonal anti-Peroxisomal N1-acetyl-spermine/spermidine oxidase (260-340 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAOX |
| Gene ID: | 196743 |
| Uniprot ID: | PAOX_HUMAN |
| Immunogen: | Synthesized peptide derived from PAOX at the amino acid range 260-340 |
| Immunogen Region: | 260-340 aa |
| Specificity: | PAOX Polyclonal Antibody detects endogenous levels of PAOX protein. |
| Function | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
| Protein Name | Peroxisomal N(1-Acetyl-Spermine/Spermidine OxidasePolyamine Oxidase |
| Database Links | Reactome: R-HSA-141334Reactome: R-HSA-351200Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeCytoplasm |
| Alternative Antibody Names | Anti-Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase antibodyAnti-Polyamine Oxidase antibodyAnti-PAOX antibodyAnti-PAO antibodyAnti-UNQ1923 antibodyAnti-PRO4398 antibody |
Information sourced from Uniprot.org
