Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Pan-Pan-Keratin (150-220 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KRT2 |
Gene ID: |
3849 |
Uniprot ID: |
K22E_HUMAN |
Immunogen Region: |
150-220 aa |
Specificity: |
The antibody detects endogenous Keratin-pan |
Immunogen: |
Synthetic peptide from the human protein at the amino acid range 150-220 |
Function | Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins. Plays a role in the establishment of the epidermal barrier on plantar skin. |
Protein Name | Keratin - Type Ii Cytoskeletal 2 EpidermalCytokeratin-2eCk-2eEpithelial Keratin-2eKeratin-2 EpidermisKeratin-2eK2eType-Ii Keratin Kb2 |
Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 2 Epidermal antibodyAnti-Cytokeratin-2e antibodyAnti-Ck-2e antibodyAnti-Epithelial Keratin-2e antibodyAnti-Keratin-2 Epidermis antibodyAnti-Keratin-2e antibodyAnti-K2e antibodyAnti-Type-Ii Keratin Kb2 antibodyAnti-KRT2 antibodyAnti-KRT2A antibodyAnti-KRT2E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance