| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PAM/PAL (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 100kDa band observed in Human Kidney lysates (calculated MW of 101kDa according to preproprotein NP_620121.1). Recommended concentration: 0.3-1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PAM |
| Gene ID: | 5066 |
| Uniprot ID: | AMD_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_000910.2; NP_620121.1; NP_620176.1; NP_620177.1 |
| Specificity: | This antibody is expected to recognise all reported isoforms (NP_000910.2; NP_620121.1; NP_620176.1 and NP_620177.1). |
| Immunogen Sequence: | DQEKEDDGSESEE |
| Protein Name | Peptidyl-Glycine Alpha-Amidating MonooxygenasePam Includes - Peptidylglycine Alpha-Hydroxylating MonooxygenasePhm - Peptidyl-Alpha-Hydroxyglycine Alpha-Amidating LyasePeptidylamidoglycolate LyasePal |
| Cellular Localisation | Cytoplasmic VesicleSecretory Vesicle MembraneSingle-Pass Membrane ProteinSecretory GranulesIsoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: MembraneIsoform 3: SecretedSecreted From Secretory GranulesIsoform 4: Secreted |
| Alternative Antibody Names | Anti-Peptidyl-Glycine Alpha-Amidating Monooxygenase antibodyAnti-Pam Includes - Peptidylglycine Alpha-Hydroxylating Monooxygenase antibodyAnti-Phm - Peptidyl-Alpha-Hydroxyglycine Alpha-Amidating Lyase antibodyAnti-Peptidylamidoglycolate Lyase antibodyAnti-Pal antibodyAnti-PAM antibody |
Information sourced from Uniprot.org