| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PALM (1-387) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PALM |
| Gene ID: |
5064 |
| Uniprot ID: |
PALM_HUMAN |
| Immunogen Region: |
1-387 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-387 of human PALM (NP_002570.2). |
| Immunogen Sequence: |
MEVLAAETTSQQERLQAIAE KRKRQAEIENKRRQLEDERR QLQHLKSKALRERWLLEGTP SSASEGDEDLRRQMQDDEQK TRLLEDSVSRLEKEIEVLER GDSAPATAKENAAAPSPVRA PAPSPAKEERKTEVVMNSQQ TPVGTPKDKRVSNTPLRTVD GSPMMKAAMYSVEITVEKDK VTGETRVLSSTTLLPRQPLP LGIKVYEDETKVVHAVDGTA ENGIHPLSSSEVDELIHKA |
| Tissue Specificity | Widely expressed with highest expression in brain and testis and intermediate expression in heart and adrenal gland. |
| Function | Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. |
| Protein Name | Paralemmin-1Paralemmin |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCell ProjectionFilopodium MembraneAxonDendriteDendritic SpineBasolateral Cell MembraneApicolateral Cell MembraneTranslocation To The Plasma Membrane Is Enhanced Upon Stimulation Of Neuronal Activity |
| Alternative Antibody Names | Anti-Paralemmin-1 antibodyAnti-Paralemmin antibodyAnti-PALM antibodyAnti-KIAA0270 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
