Anti-PAH antibody (1-290) (STJ24886)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PAH (1-290) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAH |
| Gene ID | 5053 |
| Uniprot ID | PH4H_HUMAN |
| Immunogen Region | 1-290 |
| Immunogen Sequence | MSTAVLENPGLGRKLSDFGQ ETSYIEDNCNQNGAISLIFS LKEEVGALAKVLRLFEENDV NLTHIESRPSRLKKDEYEFF THLDKRSLPALTNIIKILRH DIGATVHELSRDKKKDTVPW FPRTIQELDRFANQILSYGA ELDADHPGFKDPVYRARRKQ FADIAYNYRHGQPIPRVEYM EEEKKTWGTVFKTLKSLYKT HACYEYNHIFPLLEKYCGFH EDNIPQLEDVSQFLQTCTG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human PAH (NP_000268.1). |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-16 increases basal activity and facilitates activation by the substrate phenylalanine. |
| Function | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. |
| Protein Name | Phenylalanine-4-HydroxylasePahPhe-4-Monooxygenase |
| Database Links | Reactome: R-HSA-2160456Reactome: R-HSA-8964208 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phenylalanine-4-Hydroxylase antibodyAnti-Pah antibodyAnti-Phe-4-Monooxygenase antibodyAnti-PAH antibody |
Information sourced from Uniprot.org