Anti-PAFAH2 antibody (STJA0007422)

SKU:
STJA0007422
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Platelet-activating factor acetylhydrolase 2, cytoplasmic is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PAFAH2
Gene ID: 5051
Uniprot ID: PAFA2_HUMAN
Specificity: This antibody detects endogenous levels of PAFAH2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human PAFAH2
Function Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation. Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF. Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position.
Protein Name Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic
Paf -Lysophospholipid Transacetylase
Paf -Sphingosine Transacetylase
Platelet-Activating Factor Acetyltransferase Pafah2
Serine-Dependent Phospholipase A2
Sd-Pla2
Hsd-Pla2
Database Links Reactome: R-HSA-418346
Cellular Localisation Cytoplasm
Membrane
Lipid-Anchor
Endoplasmic Reticulum Membrane
In Resting Cells
Localizes To Intracellular Membranes And Cytoplasm
Translocates From The Cytoplasm To Intracellular Membranes Upon Oxidative Stress
Alternative Antibody Names Anti-Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic antibody
Anti-Paf -Lysophospholipid Transacetylase antibody
Anti-Paf -Sphingosine Transacetylase antibody
Anti-Platelet-Activating Factor Acetyltransferase Pafah2 antibody
Anti-Serine-Dependent Phospholipase A2 antibody
Anti-Sd-Pla2 antibody
Anti-Hsd-Pla2 antibody
Anti-PAFAH2 antibody

Information sourced from Uniprot.org

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