Anti-p57 Kip2 antibody [R07-8B7] (STJA0035313)

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STJA0035313
£133.50 - £281.50
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Host: Rabbit
Applications: WB/IHC-P/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-p57 Kip2 for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R07-8B7
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: CDKN1C
Gene ID: 1028
Uniprot ID: CDN1C_HUMAN
Immunogen: A synthetic peptide of human p57 Kip2
Tissue Specificity Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
Function Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Protein Name Cyclin-Dependent Kinase Inhibitor 1c
Cyclin-Dependent Kinase Inhibitor P57
P57kip2
Database Links Reactome: R-HSA-69231
Reactome: R-HSA-9661069
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Cyclin-Dependent Kinase Inhibitor 1c antibody
Anti-Cyclin-Dependent Kinase Inhibitor P57 antibody
Anti-P57kip2 antibody
Anti-CDKN1C antibody
Anti-KIP2 antibody

Information sourced from Uniprot.org

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