| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | P2RX5 |
| Gene ID: | 5026 |
| Uniprot ID: | P2RX5_HUMAN |
| Immunogen Region: | 341-422 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 341-422 of human P2RX5 (NP_002552.2). |
| Immunogen Sequence: | KKREFYRDKKYEEVRGLEDS SQEAEDEASGLGLSEQLTSG PGLLGMPEQQELQEPPEAKR GSSSQKGNGSVCPQLLEPHR ST |
| Tissue Specificity | Expressed at high levels in brain and immune system. |
| Function | Isoform 6: ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Unlike, other P2RX receptors, the P2X5 receptor is also permeable to chloride. May play a supporting role in the inflammatory response. Isoform 1: Non-functional. |
| Protein Name | P2x Purinoceptor 5P2x5Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Isoform 6: Cell MembraneMulti-Pass Membrane ProteinThe Absence Of The Exon 10-Encoded Amino Acids Substantially Results In Subunit Aggregation And Retention In The Cell Cytoplasm |
| Alternative Antibody Names | Anti-P2x Purinoceptor 5 antibodyAnti-P2x5 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX5 antibodyAnti-P2X5 antibodyAnti-P2X5FL antibody |
Information sourced from Uniprot.org