| Host: | Mouse |
| Applications: | ELISA/WB/ICC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-P-Cadherin (N-Term) for use in ELISA, WB and ICC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | M596 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: | Protein A Purified |
| Dilution Range: | WB 1:1000ICC 1:100 |
| Storage Instruction: | Storage at-20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20°C. |
| Gene Symbol: | CDH3 |
| Gene ID: | 1001 |
| Uniprot ID: | CADH3_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | The P-cadherin antibody detects a 120 kDa* protein corresponding to endogenous P-Cadherin expressed in human A431 cells. |
| Immunogen: | Clone (M596) was generated from a recombinant protein containing amino acids in the N-terminal region of human P-Cadherin. This sequence is highly conserved in mouse and rat P-cadherin. |
| Immunogen Sequence: | Human |
| Tissue Specificity | Expressed in some normal epithelial tissues and in some carcinoma cell lines. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-3Placental CadherinP-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-3 antibodyAnti-Placental Cadherin antibodyAnti-P-Cadherin antibodyAnti-CDH3 antibodyAnti-CDHP antibody |
Information sourced from Uniprot.org