| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1500-1:6000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CDH3 |
| Gene ID: | 1001 |
| Uniprot ID: | CADH3_HUMAN |
| Immunogen Region: | 108-654 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 108-654 of human P-cadherin (NP_001784.2). |
| Immunogen Sequence: | DWVVAPISVPENGKGPFPQR LNQLKSNKDRDTKIFYSITG PGADSPPEGVFAVEKETGWL LLNKPLDREEIAKYELFGHA VSENGASVEDPMNISIIVTD QNDHKPKFTQDTFRGSVLEG VLPGTSVMQVTATDEDDAIY TYNGVVAYSIHSQEPKDPHD LMFTIHRSTGTISVISSGLD REKVPEYTLTIQATDMDGDG STTTAVAVVEILDANDNAPM FDPQKYEAHVPENAVGHEV |
| Tissue Specificity | Expressed in some normal epithelial tissues and in some carcinoma cell lines. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-3Placental CadherinP-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-3 antibodyAnti-Placental Cadherin antibodyAnti-P-Cadherin antibodyAnti-CDH3 antibodyAnti-CDHP antibody |
Information sourced from Uniprot.org