| Short Description : | Rabbit polyclonal OTUB2 (1-73) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OTUB2 |
| Gene ID: | 78990 |
| Uniprot ID: | OTUB2_HUMAN |
| Immunogen Region: | 1-73 |
| Immunogen Sequence: | MSETSFNLISEKCDILSILR DHPENRIYRRKIEELSKRFT AIRKTKGDGNCFYRALGYSY LESLLGKSREIFK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-73 of human OTUB2 (NP_075601.1). |
| Tissue Specificity | Widely expressed. Expressed at higher level in brain. |
| Function | Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains. |
| Protein Name | Ubiquitin Thioesterase Otub2Deubiquitinating Enzyme Otub2Otu Domain-Containing Ubiquitin Aldehyde-Binding Protein 2Otubain-2Ubiquitin-Specific-Processing Protease Otub2 |
| Database Links | Reactome: R-HSA-5689896 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ubiquitin Thioesterase Otub2 antibodyAnti-Deubiquitinating Enzyme Otub2 antibodyAnti-Otu Domain-Containing Ubiquitin Aldehyde-Binding Protein 2 antibodyAnti-Otubain-2 antibodyAnti-Ubiquitin-Specific-Processing Protease Otub2 antibodyAnti-OTUB2 antibodyAnti-C14orf137 antibodyAnti-OTB2 antibodyAnti-OTU2 antibody |
Information sourced from Uniprot.org
