| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Oxysterol-binding protein-related protein 6 (260-340 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OSBPL6 |
| Gene ID: | 114880 |
| Uniprot ID: | OSBL6_HUMAN |
| Immunogen Region: | 260-340 aa |
| Specificity: | OSBL6 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 260-340 |
| Function | Regulates cellular transport and efflux of cholesterol. Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane. Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid. Weakly binds 25-hydroxycholesterol. |
| Protein Name | Oxysterol-Binding Protein-Related Protein 6Orp-6Osbp-Related Protein 6 |
| Database Links | Reactome: R-HSA-192105 |
| Cellular Localisation | CytoplasmCytosolEndoplasmic Reticulum MembranePeripheral Membrane ProteinNucleus EnvelopeCell MembraneEndosome MembraneCo-Localizes With Osbpl3 At Contact Sites Between The Plasma Membrane And The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 6 antibodyAnti-Orp-6 antibodyAnti-Osbp-Related Protein 6 antibodyAnti-OSBPL6 antibodyAnti-ORP6 antibody |
Information sourced from Uniprot.org