Anti-OSBPL2 antibody (50-100) (STJA0006979)

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STJA0006979
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Short Description :Rabbit polyclonal anti-Oxysterol-binding protein-related protein 2 (50-100) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:OSBPL2
Gene ID:9885
Uniprot ID:OSBL2_HUMAN
Immunogen:Synthesized peptide derived from human OSBPL2
Immunogen Region:50-100
Specificity:This antibody detects endogenous levels of OSBPL2 at Human, Mouse
Function Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).
Protein Name Oxysterol-Binding Protein-Related Protein 2
Orp-2
Osbp-Related Protein 2
Database Links Reactome: R-HSA-192105
Cellular Localisation Cytoplasm
Cytosol
Lipid Droplet
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Detected On The Surface Of Cytosolic Lipid Droplets
Recruited To The Cell Membrane By Phosphatidylinositol-Phosphate Binding
Alternative Antibody Names Anti-Oxysterol-Binding Protein-Related Protein 2 antibody
Anti-Orp-2 antibody
Anti-Osbp-Related Protein 2 antibody
Anti-OSBPL2 antibody
Anti-KIAA0772 antibody
Anti-ORP2 antibody

Information sourced from Uniprot.org

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