| Function | Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage. Weakly binds 25-hydroxycholesterol. Interacts with OSBPL9 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex. |
| Protein Name | Oxysterol-Binding Protein-Related Protein 11Orp-11Osbp-Related Protein 11 |
| Database Links | Reactome: R-HSA-9013407 |
| Cellular Localisation | Late Endosome MembraneGolgi ApparatusTrans-Golgi Network MembraneLocalizes At The Golgi-Late Endosome Interface |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 11 antibodyAnti-Orp-11 antibodyAnti-Osbp-Related Protein 11 antibodyAnti-OSBPL11 antibodyAnti-ORP11 antibodyAnti-OSBP12 antibody |
Information sourced from Uniprot.org
