Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-OSBP antibody (284-334 aa) (STJ194261)

SKU:
STJ194261
£48.00 - £252.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Oxysterol-binding protein 1 (284-334 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OSBP
Gene ID: 5007
Uniprot ID: OSBP1_HUMAN
Immunogen Region: 284-334 aa
Specificity: This antibody detects endogenous levels of OSBP1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human OSBP1 at the amino acid range 284-334
Function Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability.
Protein Name Oxysterol-Binding Protein 1
Database Links Reactome: R-HSA-1660661
Reactome: R-HSA-192105
Cellular Localisation Cytoplasm
Cytosol
Perinuclear Region
Golgi Apparatus Membrane
Peripheral Membrane Protein
Endoplasmic Reticulum Membrane
Golgi Apparatus
Trans-Golgi Network
Predominantly Cytosolic
Alternative Antibody Names Anti-Oxysterol-Binding Protein 1 antibody
Anti-OSBP antibody
Anti-OSBP1 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ193477 Anti-OTULIN antibody (284-334 aa) (STJ193477) Rabbit Polyclonal Human/Mouse WB
STJA0006375 Anti-PPM1A antibody (284-334) (STJA0006375) Rabbit Polyclonal Human/Mouse/Rat WB
STJ93547 Anti-HM74 antibody (285-334 aa) (STJ93547) Rabbit Polyclonal Human/Mouse/Rat WB/IF/ELISA
STJ92274 Anti-CHAT antibody (334-383 aa) (STJ92274) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ194654 Anti-NIBAN1 antibody (334-384 aa) (STJ194654) Rabbit Polyclonal Human/Mouse/Rat WB
STJ70683 Anti-OSBP antibody (Internal) (STJ70683) Goat Polyclonal Human/Mouse/Rat/Dog/Cow Pep-ELISA/WB
STJ24872 Anti-OSBP antibody (508-807) (STJ24872) Rabbit Polyclonal Human/Mouse/Rat WB/IF/ICC/ELISA
STJ194474 Anti-SRPX antibody (234-284 aa) (STJ194474) Rabbit Polyclonal Human/Mouse/Rat WB
STJ197551 Anti-OR8U8 antibody (234-284 aa) (STJ197551) Rabbit Polyclonal Human/Rat/Mouse WB
!