| Short Description : | Mouse monoclonal anti-Ornithine Decarboxylase/ODC1 (1-461aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB/ICC/IF |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | AT9B3 |
| Isotype: | IgG2bk |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | By protein-A affinity chromatography |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ODC1 |
| Gene ID: | 4953 |
| Uniprot ID: | DCOR_HUMAN |
| Accession Number: | NP_002530 |
| Immunogen: | Recombinant human ODC1 (1-461aa) purified from E. coli |
| Immunogen Region: | 1-461aa |
| Post Translational Modifications | S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues. |
| Function | Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. |
| Protein Name | Ornithine DecarboxylaseOdc |
| Database Links | Reactome: R-HSA-350562Reactome: R-HSA-351202 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ornithine Decarboxylase antibodyAnti-Odc antibodyAnti-ODC1 antibody |
Information sourced from Uniprot.org
