| Host: | Rabbit |
| Applications: | IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Olfactory receptor 10J5 (220-269) is suitable for use in Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OR10J5 |
| Gene ID: | 127385 |
| Uniprot ID: | O10J5_HUMAN |
| Immunogen Region: | 220-269 |
| Specificity: | Olfactory receptor 10J5 Polyclonal Antibody detects endogenous levels of Olfactory receptor 10J5 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human OR10J5. AA range:220-269 |
| Tissue Specificity | Expressed in both the aorta, the coronary artery and umbilical vein endothelial cells (HUVECs) (at protein level). |
| Function | Olfactory receptor. Activated by the synthetic floral odorant, lyral, and by alpha-cedrene, a sesquiterpene constituent of cedarwood oil. Its activation increases intracellular Ca(2+). Acts as a key regulator of myogenesis through its actions on cell migration and adhesion by activating the Ca(2+)-dependent AKT signal transduction pathway. Acts also as a regulator of angiogenesis. Moreover, plays a role in the regulation of lipid accumulation in hepatocytes via the cAMP-PKA pathway. May be involved in sperm chemotaxis and motility. |
| Protein Name | Olfactory Receptor 10j5Olfactory Receptor Or1-28 |
| Database Links | Reactome: R-HSA-381753Reactome: R-HSA-9752946 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Olfactory Receptor 10j5 antibodyAnti-Olfactory Receptor Or1-28 antibodyAnti-OR10J5 antibody |
Information sourced from Uniprot.org