| Host: | Rabbit |
| Applications: | IHC/WB/FC |
| Reactivity: | Human/Rat/Mouse/Marmoset |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Olig2 is suitable for use in Immunohistochemistry, Western Blot and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB, Flow Cyt. A dilution of 1:250 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Olig2 |
| Gene ID: | 50913 |
| Uniprot ID: | OLIG2_MOUSE |
| Specificity: | Specific for Olig2. |
| Immunogen: | A synthetic peptide from human Olig2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Function | Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. |
| Protein Name | Oligodendrocyte Transcription Factor 2Oligo2 |
| Cellular Localisation | NucleusCytoplasmThe Nls Contained In The Bhlh Domain Could Be Masked In The Native Form And Translocation To The Nucleus Could Be Mediated By Interaction Either With Class E Bhlh Partner Protein Or With Nkx2-2 |
| Alternative Antibody Names | Anti-Oligodendrocyte Transcription Factor 2 antibodyAnti-Oligo2 antibodyAnti-Olig2 antibody |
Information sourced from Uniprot.org