Anti-OLFM2 antibody (STJA0009652)

SKU:
STJA0009652
£48.00 - £252.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Noelin-2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OLFM2
Gene ID: 93145
Uniprot ID: NOE2_HUMAN
Specificity: This antibody detects endogenous levels of OLFM2 at Human, Mouse
Immunogen: Synthesized peptide derived from human OLFM2
Post Translational Modifications N-glycosylated.
Function Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization. Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli. SMC phenotypic plasticity is essential for vascular development and remodeling.
Protein Name Noelin-2
Olfactomedin-2
Cellular Localisation Secreted
Synapse
Membrane
Nucleus
Cytoplasm
Nuclear Localization Is Induced By Tgf-Beta
Alternative Antibody Names Anti-Noelin-2 antibody
Anti-Olfactomedin-2 antibody
Anti-OLFM2 antibody
Anti-NOE2 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ90000 Anti-ACR antibody (40-120 aa) (STJ90000) Rabbit Polyclonal Human/Rat/Mouse WB/IHC/IF/ELISA
STJA0003689 Anti-GRM7 antibody (STJA0003689) Rabbit Polyclonal Mouse/Rat/Bovine/Canine/Human/Non-Human Primates/Zebrafish WB
STJA0005709 Anti-Antp antibody (STJA0005709) Rabbit Polyclonal All WB
STJA0005741 Anti-DCBLD2 antibody (STJA0005741) Rabbit Polyclonal Human/Mouse/Rat WB
STJA0005593 Anti-SPTAN1 antibody (STJA0005593) Rabbit Polyclonal Human/Mouse/Rat WB
!