| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000 IHC-P:1:100-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OGN |
| Gene ID: | 4969 |
| Uniprot ID: | MIME_HUMAN |
| Immunogen Region: | 20-298 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-298 of human Osteoglycin (OGN) (NP_054776.1). |
| Immunogen Sequence: | APPTQQDSRIIYDYGTDNFE ESIFSQDYEDKYLDGKNIKE KETVIIPNEKSLQLQKDEAI TPLPPKKENDEMPTCLLCVC LSGSVYCEEVDIDAVPPLPK ESAYLYARFNKIKKLTAKDF ADIPNLRRLDFTGNLIEDIE DGTFSKLSLLEELSLAENQL LKLPVLPPKLTLFNAKYNKI KSRGIKANAFKKLNNLTFLY LDHNALESVPLNLPESLRVI HLQFNNIASITDDTFCKAN |
| Tissue Specificity | Bone. |
| Post Translational Modifications | O-glycosylated with a core 1 or possibly core 8 glycan. Contains keratan sulfate. |
| Function | Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. |
| Protein Name | Mimecan Osteoglycin Osteoinductive Factor Oif |
| Database Links | Reactome: R-HSA-2022854 Reactome: R-HSA-2022857 Reactome: R-HSA-3656225 Reactome: R-HSA-3656243 Reactome: R-HSA-3656244 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
| Alternative Antibody Names | Anti-Mimecan antibody Anti-Osteoglycin antibody Anti-Osteoinductive Factor antibody Anti-Oif antibody Anti-OGN antibody Anti-OIF antibody Anti-SLRR3A antibody |
Information sourced from Uniprot.org