• Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-OGG1 antibody (STJ193142)

SKU:
STJ193142

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-N-glycosylase/DNA lyase is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OGG1
Gene ID: 4968
Uniprot ID: OGG1_HUMAN
Specificity: OGG1 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
Protein Name N-Glycosylase/Dna Lyase Includes - 8-Oxoguanine Dna Glycosylase - Dna-(Apurinic Or Apyrimidinic Site Lyase
Ap Lyase
Database Links Reactome: R-HSA-110328
Reactome: R-HSA-110329
Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-110357
Reactome: R-HSA-5649702
Reactome: R-HSA-9656255
Reactome: R-HSA-9656256
Reactome: R-HSA-9657050 O15527-4
Cellular Localisation Nucleus
Nucleoplasm
Nucleus Speckle
Nucleus Matrix
Together With Apex1 Is Recruited To Nuclear Speckles In Uva-Irradiated Cells
Isoform 1a: Nucleus
Isoform 2a: Mitochondrion
Alternative Antibody Names Anti-N-Glycosylase/Dna Lyase Includes - 8-Oxoguanine Dna Glycosylase - Dna-(Apurinic Or Apyrimidinic Site Lyase antibody
Anti-Ap Lyase antibody
Anti-OGG1 antibody
Anti-MMH antibody
Anti-MUTM antibody
Anti-OGH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance