| Short Description : | Rabbit monoclonal anti-ODC1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R05-9Q7 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000 |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | ODC1 |
| Gene ID: | 4953 |
| Uniprot ID: | DCOR_HUMAN |
| Immunogen: | A synthesized peptide derived from human Ornithine Decarboxylase |
| Post Translational Modifications | S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues. |
| Function | Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. |
| Protein Name | Ornithine DecarboxylaseOdc |
| Database Links | Reactome: R-HSA-350562Reactome: R-HSA-351202 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ornithine Decarboxylase antibodyAnti-Odc antibodyAnti-ODC1 antibody |
Information sourced from Uniprot.org
