Anti-OCT6/POU3F1 antibody (Internal) (STJ71024)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-OCT6/POU3F1 (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Preliminary experiments in lysates of Human Brain (Cerebellum, Hippocampus, Frontal Cortex) , Mouse Brain, Rat Brain and Rat Spinal Cord gave no specific signal but low background (at a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | POU3F1 |
| Gene ID | 5453 |
| Uniprot ID | PO3F1_HUMAN |
| Accession Number | NP_002690.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | GHPPMDDVYAPGE |
Additional Info
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes. |
| Protein Name | Pou Domain - Class 3 - Transcription Factor 1Octamer-Binding Protein 6Oct-6Octamer-Binding Transcription Factor 6Otf-6Pou Domain Transcription Factor Scip |
| Database Links | Reactome: R-HSA-9619665Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 3 - Transcription Factor 1 antibodyAnti-Octamer-Binding Protein 6 antibodyAnti-Oct-6 antibodyAnti-Octamer-Binding Transcription Factor 6 antibodyAnti-Otf-6 antibodyAnti-Pou Domain Transcription Factor Scip antibodyAnti-POU3F1 antibodyAnti-OCT6 antibodyAnti-OTF6 antibody |
Information sourced from Uniprot.org