| Short Description : | Goat polyclonal antibody anti-OCIL (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence, Flow Cytometry and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IF/FC/IHC |
| Host: | Goat |
| Reactivity: | Human/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 30-35kDa band observed in lysates of histiocytic lymphoma cell line U937 (calculated MW of 22.3kDa according to NP_001004419.1). This molecular weight is routinely observed by o |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CLEC2D |
| Gene ID: | 29121 |
| Uniprot ID: | CLC2D_HUMAN |
| Accession Number: | NP_037401.1; NP_001004419.1; NP_001184246.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | LLRYKGPSDH |
| Specificity: | This antibody is expected to recognize all isoforms (NP_037401.1; NP_001004419.1; NP_001184246.1). |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. |
| Protein Name | C-Type Lectin Domain Family 2 Member DLectin-Like Nk Cell ReceptorLectin-Like Transcript 1Llt-1Osteoclast Inhibitory Lectin |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2: Endoplasmic ReticulumIsoform 4: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 2 Member D antibodyAnti-Lectin-Like Nk Cell Receptor antibodyAnti-Lectin-Like Transcript 1 antibodyAnti-Llt-1 antibodyAnti-Osteoclast Inhibitory Lectin antibodyAnti-CLEC2D antibodyAnti-CLAX antibodyAnti-LLT1 antibodyAnti-OCIL antibody |
Information sourced from Uniprot.org
