Anti-OBI1 antibody (STJA0008902)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RNF219
General Information
| Short Description | Rabbit polyclonal anti-ORC ubiquitin ligase 1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OBI1 |
| Gene ID | 79596 |
| Uniprot ID | OBI1_HUMAN |
| Immunogen | Synthesized peptide derived from human RNF219 |
| Specificity | This antibody detects endogenous levels of RNF219 at Human |
Additional Info
| Function | E3 ubiquitin ligase essential for DNA replication origin activation during S phase. Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase. |
| Protein Name | Orc Ubiquitin Ligase 1Obi1Ring Finger Protein 219 |
| Database Links | |
| Cellular Localisation | ChromosomeAssociation To Chromatin Is Cell Cycle-RegulatedAbsent From Mitotic ChromosomesIs Associated With Chromatin From G1 And Partially Released From Chromatin From Mid S-Phase |
| Alternative Antibody Names | Anti-Orc Ubiquitin Ligase 1 antibodyAnti-Obi1 antibodyAnti-Ring Finger Protein 219 antibodyAnti-OBI1 antibodyAnti-C13orf7 antibodyAnti-RNF219 antibody |
Information sourced from Uniprot.org