Anti-NUP107 antibody (700-800) [S4133RM] (STJ11104133)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11104133
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General Information

Short DescriptionRabbit monoclonal Nuclear Pore Complex Protein Nup107 (700-800) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS4133RM
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:100-1:500
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolNUP107
Gene ID57122
Uniprot IDNU107_HUMAN
Immunogen Region700-800
Immunogen SequenceLASKKHEAAKEVFVKIPQDS IAEIYNQCEEQGMESPLPAE DDNAIREHLCIRAYLEAHET FNEWFKHMNSVPQKPALIPQ PTFTEKVAHEHKEKKYEMDF G
SpecificityA synthetic peptide corresponding to a sequence within amino acids 700-800 of human Nup107 (P57740).

Additional Info

Tissue Specificity Ubiquitously expressed in fetal and adult tissues.
Function Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis.
Protein Name Nuclear Pore Complex Protein Nup107
107 Kda Nucleoporin
Nucleoporin Nup107
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-141444
Reactome: R-HSA-159227
Reactome: R-HSA-159230
Reactome: R-HSA-159231
Reactome: R-HSA-159236
Reactome: R-HSA-165054
Reactome: R-HSA-168271
Reactome: R-HSA-168276
Reactome: R-HSA-168325
Reactome: R-HSA-168333
Reactome: R-HSA-170822
Reactome: R-HSA-180746
Reactome: R-HSA-180910
Reactome: R-HSA-191859
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-3108214
Reactome: R-HSA-3232142
Reactome: R-HSA-3301854
Reactome: R-HSA-3371453
Reactome: R-HSA-4085377
Reactome: R-HSA-4551638
Reactome: R-HSA-4570464
Reactome: R-HSA-4615885
Reactome: R-HSA-5578749
Reactome: R-HSA-5619107
Reactome: R-HSA-5663220
Reactome: R-HSA-6784531
Reactome: R-HSA-68877
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Reactome: R-HSA-9615933
Reactome: R-HSA-9648025
Reactome: R-HSA-9705671
Cellular Localisation Nucleus Membrane
Nucleus
Nuclear Pore Complex
Chromosome
Centromere
Kinetochore
Located On Both The Cytoplasmic And Nuclear Sides Of The Npc Core Structure
During Mitosis
Localizes To The Kinetochores
Dissociates From The Dissasembled Npc Structure Late During Prophase Of Mitosis
Alternative Antibody Names Anti-Nuclear Pore Complex Protein Nup107 antibody
Anti-107 Kda Nucleoporin antibody
Anti-Nucleoporin Nup107 antibody
Anti-NUP107 antibody

Information sourced from Uniprot.org

Citations

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