Anti-Nucleostemin antibody [R07-2Q3] (STJA0036918)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Nucleostemin
STJA0036918
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General Information

Short DescriptionRabbit monoclonal anti-Nucleostemin for use in WB, ICC, IF and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ICC/IF/FC
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR07-2Q3
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity Chromatography
Dilution RangeWB 1:500-1:1000
IF 1:50-1:200
FC 1:50-1:100
FormulationRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolGNL3
Gene ID26354
Uniprot IDGNL3_HUMAN
ImmunogenA synthesized peptide derived from human Nucleostemin

Additional Info

Tissue Specificity Increased levels in lung tissue in cancer patients.
Function May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Protein Name Guanine Nucleotide-Binding Protein-Like 3
E2-Induced Gene 3 Protein
Novel Nucleolar Protein 47
Nnp47
Nucleolar Gtp-Binding Protein 3
Nucleostemin
Database Links Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Shuttles Between The Nucleus And Nucleolus
Alternative Antibody Names Anti-Guanine Nucleotide-Binding Protein-Like 3 antibody
Anti-E2-Induced Gene 3 Protein antibody
Anti-Novel Nucleolar Protein 47 antibody
Anti-Nnp47 antibody
Anti-Nucleolar Gtp-Binding Protein 3 antibody
Anti-Nucleostemin antibody
Anti-GNL3 antibody
Anti-E2IG3 antibody
Anti-NS antibody

Information sourced from Uniprot.org

Citations

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