| Host: | Rabbit |
| Applications: | WB/ICC/IF/FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Nucleostemin for use in WB, ICC, IF and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R07-2Q3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IF 1:50-1:200FC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | GNL3 |
| Gene ID: | 26354 |
| Uniprot ID: | GNL3_HUMAN |
| Immunogen: | A synthesized peptide derived from human Nucleostemin |
| Tissue Specificity | Increased levels in lung tissue in cancer patients. |
| Function | May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. |
| Protein Name | Guanine Nucleotide-Binding Protein-Like 3E2-Induced Gene 3 ProteinNovel Nucleolar Protein 47Nnp47Nucleolar Gtp-Binding Protein 3Nucleostemin |
| Database Links | Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusShuttles Between The Nucleus And Nucleolus |
| Alternative Antibody Names | Anti-Guanine Nucleotide-Binding Protein-Like 3 antibodyAnti-E2-Induced Gene 3 Protein antibodyAnti-Novel Nucleolar Protein 47 antibodyAnti-Nnp47 antibodyAnti-Nucleolar Gtp-Binding Protein 3 antibodyAnti-Nucleostemin antibodyAnti-GNL3 antibodyAnti-E2IG3 antibodyAnti-NS antibody |
Information sourced from Uniprot.org