Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (28-77) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NUCKS1 |
Gene ID: |
64710 |
Uniprot ID: |
NUCKS_HUMAN |
Immunogen Region: |
28-77 |
Specificity: |
NUCKS Polyclonal Antibody detects endogenous levels of NUCKS protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human NUCKS1. AA range:28-77 |
Tissue Specificity | Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung. |
Post Translational Modifications | Phosphorylated in an ATM-dependent manner in response to DNA damage. Phosphorylated by CDK1 and casein kinase. |
Function | Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1. |
Protein Name | Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1P1 |
Cellular Localisation | NucleusChromosome |
Alternative Antibody Names | Anti-Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1 antibodyAnti-P1 antibodyAnti-NUCKS1 antibodyAnti-NUCKS antibodyAnti-JC7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance