| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NUCB2 (321-420) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NUCB2 |
| Gene ID: |
4925 |
| Uniprot ID: |
NUCB2_HUMAN |
| Immunogen Region: |
321-420 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 321-420 of human NUCB2 (NP_005004.1). |
| Immunogen Sequence: |
ATEKKEFLEPDSWETLDQQQ FFTEEELKEYENIIALQENE LKKKADELQKQKEELQRQHD QLEAQKLEYHQVIQQMEQKK LQQGIPPSGPAGELKFEPHI |
| Tissue Specificity | Predominantly expressed in spleen, testis and normal stomach. |
| Function | Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. |
| Protein Name | Nucleobindin-2Dna-Binding Protein NefaEpididymis Secretory Protein Li 109Gastric Cancer Antigen Zg4Prepronesfatin Cleaved Into - Nesfatin-1 |
| Cellular Localisation | Golgi ApparatusMembranePeripheral Membrane ProteinCytoplasmSecretedEndoplasmic ReticulumNucleus EnvelopeGolgi Retention Is Mediated By Its N-Terminal RegionNesfatin-1: Secreted |
| Alternative Antibody Names | Anti-Nucleobindin-2 antibodyAnti-Dna-Binding Protein Nefa antibodyAnti-Epididymis Secretory Protein Li 109 antibodyAnti-Gastric Cancer Antigen Zg4 antibodyAnti-Prepronesfatin Cleaved Into - Nesfatin-1 antibodyAnti-NUCB2 antibodyAnti-NEFA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
