Anti-NUCB2 antibody (321-420) (STJ114516)

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STJ114516
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NUCB2
Gene ID: 4925
Uniprot ID: NUCB2_HUMAN
Immunogen Region: 321-420
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 321-420 of human NUCB2 (NP_005004.1).
Immunogen Sequence: ATEKKEFLEPDSWETLDQQQ FFTEEELKEYENIIALQENE LKKKADELQKQKEELQRQHD QLEAQKLEYHQVIQQMEQKK LQQGIPPSGPAGELKFEPHI
Tissue Specificity Predominantly expressed in spleen, testis and normal stomach.
Function Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Protein Name Nucleobindin-2
Dna-Binding Protein Nefa
Epididymis Secretory Protein Li 109
Gastric Cancer Antigen Zg4
Prepronesfatin Cleaved Into - Nesfatin-1
Cellular Localisation Golgi Apparatus
Membrane
Peripheral Membrane Protein
Cytoplasm
Secreted
Endoplasmic Reticulum
Nucleus Envelope
Golgi Retention Is Mediated By Its N-Terminal Region
Nesfatin-1: Secreted
Alternative Antibody Names Anti-Nucleobindin-2 antibody
Anti-Dna-Binding Protein Nefa antibody
Anti-Epididymis Secretory Protein Li 109 antibody
Anti-Gastric Cancer Antigen Zg4 antibody
Anti-Prepronesfatin Cleaved Into - Nesfatin-1 antibody
Anti-NUCB2 antibody
Anti-NEFA antibody

Information sourced from Uniprot.org